There are two "friction" pitches near the top of the upper Holt where, if you follow the blazes, lead up steep ledges with no handholds; you must rely on your boots not to slip. If they do slip, you're going to leave a lot of skin on the rock and maybe break a limb or two. It has definitely happened. However, one can bushwhack around these section with a bit of effort and less risk.
The most comparable normal hiking trails I know of are Tripyramids North Slide and the pitch above the top of the Fan in Huntington's Ravine. Neither are quite as steep, and both have at least some minimal handholds. I was most scared on the Holt, but a slip on North Slide would probably be do a lot more damage -- one could slide, roll and bounce a long way there.
Most other scrambly places, the ravine headwalls, Flume Slide, Madison Gulf, Caps Ridge, 6 Husbands, give you plenty of handholds. I've never done Owl's Head.