Don't get me started; I can talk about my canoe trips all day...
In the Adirondacks, there are certainly many opportunities to mix hiking and camping, but I can't say that I've done that more than once. The one time I did mix on the SAME trip was a year ago, when I camped at Rollins Pond (Saranac area, Adirondacks). I hiked my 46th peak (Emmons) on Thursday, hiked Goodnow Mountain (a fire tower peak) Friday, and paddled around the ponds on Saturday.
I was a paddler for many years before I hiked up my first mountain just 5 years ago, so I have many "favorite" paddle destinations.
Ontario's Algonquin Provincial Park:
Rock Lake - Pen Lake - Clydegale Lake.
Canoe Lake - Thom Thomson Lake - MacIntosh Lake.
Smoke Lake - Ragged Lake.
Canoe Lake - Otterslides - Happy Isle - Opeongo (loop).
Or just paddle up to a site on one of the arms of the big lake they call Opeongo (great for kayaks).
Adirondacks:
Cranberry Lake (Wanakena) to Dead Creek Flow (another good kayak destination).
Stillwater Reservoir (also kayaks or canoes or.... POWER BOATS).
St. Regis Canoe Area.
Fish Creek Ponds area.
Bog River -Low's Lake -Oswegatchie River-"Inlet" (traverse).
Middle Saranac Lake or Lower Saranac Lake in early May (after mid-May, there is a fee to camp on those lakes).
A day trip to the north end of Lake Placid (great views of Whiteface and more).
The Raquette River, upstream from the launch that's just East of Tupper Lake (the public launch area is referred to as "the crusher").
Or if you want a long multi-day trip... Try launching on Lake Kushaqua (east of Paul Smiths), and do a long loop through Rainbow Lake - Osgood Pond - Lower St. Regis Lake - Upper St. Regis Lake - carry into and through the St. Regis Canoe Area to Floodwood Pond - Rollins Pond - Whey Pond - Fish Creek area - Upper Saranac - Middle Saranac - Lower Saranac - Saranac River - and end up on Lake Flower in downtown Saranac Lake Village!
Some of these trips are possible with a kayak, but most involve portaging ("carries"), and are best suited for canoes.
Fun Wow!!