I wound up not doing the full loop I had planned a few weeks ago so I went up Hale from Zealand Road and then down Lend-A-Hand to Hut and then up Twinway, down Zeacliff Trail and some other meanderings. I still can't say I have a clear preference for the loop. Some considerations:
-Depending on the weather/water levels at the 3rd crossing of the Little River you may want to do the crossing early on to avoid any issues coming back later in the day if storms may bring rising water levels or the water is already high. I don't like to leave a tricky river crossing late in the day where fatigue or darkness might increase the odds of a mishap.
-The climb up to North Twin is a more rugged and more steep compared to Hale. If you like getting the vertical out of the way early I'd go that way first. Hale's vertical is similar but the footing is much better and it doesn't seem nearly as strenuous because you aren't stepping up significant amounts onto big rocks, etc.
-The col between Guyot and Zealand is very rough, climbs more than people realize given a quick glance at the map and has a quite steep section just beyond spur to Zealand summit. I generally prefer descending that section and doing the short 300' climb up to Zealand Spur versus the other way around.
-The views on this loop are definitely in favor of the Twins side of the trails IMO. You have Zeacliff outlook and some nice ledge areas heading back to Hale but after that it's pretty vanilla for a lot of miles back to the car. Lend A Hand had some minor views, wetlands and some pretty forest but it is not as dramatic as the summits of the Twins and that great outlook before you drop down into the trees heading back down. I guess weather would affect this too. If you're expecting clouds later in day hitting Twins early to get views might make more sense.
Wish I could be more definitive one way or the other. After outlining some of the above points I think I'd do Hale first. So I guess what I'm saying is flip a coin.